Competed on and won "Ted Mack's Amateur Hour" with friends at age 14
Performed as a teenager on "The Jackie Gleason Show" (CBS)
Played one season of summer stock in Durango, CO in the mid-1960s
Made TV debut on "The Danny Thomas Hour" (NBC)
Appeared in films "How Sweet It Is" and "The Savage Seven"
Played recurring role of Myrna Turner on ABC sitcom "The Odd Couple"
Debuted Laverne DeFazio character on ABC's "Happy Days"
Co-starred as tough-talking Laverne opposite Cindy Williams' perky Shirley on hit ABC sitcom "Laverne and Shirley," a spin-off of "Happy Days"
Made TV directing debut on an episode of the sitcom "Working Stiffs" (CBS)
Directed four episodes of "Laverne and Shirley" toward the end of its run
Asked by Paramount to direct feature film "Joy of Sex," starring John Belushi; Belushi was then found dead in 1982; film eventually made by Martha Coolidge two years later
Feature directorial debut, Whoopi Goldberg comedy vehicle "Jumpin' Jack Flash"
Directed Tom Hanks to his first Oscar nomination in "Big"
Feature executive producing debut, "Awakenings"; film earned a Best Picture Oscar nomination
Helmed "A League of Their Own" about the women's national baseball league; film starred Geena Davis and Hanks, and featured Rosie O'Donnell and Madonna in supporting roles
Suffered what may have been a heart attack
Began appearing with Rosie O'Donnell in a series of TV commercials for K-Mart
Signed three-year, first-look deal with Universal Pictures
Helmed "The Preacher's Wife," a remake of the 1942 film "The Bishop's Wife"; Marshall's version starred Denzel Washington and Whitney Houston
Directed the comedy-drama "Riding in Cars With Boys," starring Drew Barrymore
Played Lt. Chevetone in the drama "Stateside," starring Carrie Fisher and Rachael Leigh Cook
Received a Star on the Hollywood Walk of Fame (August)
Appeared in Albert Brooks' "Looking for Comedy in the Muslim World"
Helmed a series of Dove shorts headlined by Felicity Huffman; premiered at <i>dovenight.com</i>
Helmed two episodes of "According to Jim" (ABC), starring Jim Belushi
Directed "Women Without Men"; also co-starred with Lorraine Bracco and Dyan Cannon
Guest starred on IFC comedy series "Portlandia"
Published memoir <i>My Mother Was Nuts</i>