Moved with family to Pontiac, MI at age six following mother's death
Studied dance in teen years; acted in school plays
Moved to New York to pursue career in dance
Appeared in the independent film "A Certain Sacrifice"
Accepted into Alvin Ailey's third company; abandoned Ailey for lessons with ex-Martha Graham choreographer Pearl Lang
Met musician Dan Gilroy who taught her to play guitar, keyboards and drums
Went to Paris and studied with a vocal coach and dance instructor
Auditioned as singer-dancer with French disco singer Patrick Hernandez
After returning to New York, performed with several bands including The Breakfast Club and Emmy (her nickname)
Demonstration tape "Everybody" played at Danceteria by friendly DJ Mark Kamins; Kamins introduced her to Sire Records executive Seymour Stein, who signed her to a recording contract
Released first album, <i>Madonna</i>
First hit single, "Holiday"; song reached top 20 (peaked at No. 16)
First top 10 hit, "Borderline" (peaked at No. 10)
First No. 1 hit on the pop singles chart, "Like a Virgin"
Wrote and performed song "Gambler" for feature film "Vision Quest"; also appeared in film as bar band singer
Feature film acting debut as title character of "Desperately Seeking Susan"
Made stage acting debut in invitation-only performance of David Rabe's play "Goose and Tom-Tom," co-starring Sean Penn
First film made through her production company (Siren), "Siesta"; film directed by Mary Lambert, who directed early Madonna videos; Madonna did not appear in film
Broadway debut in "Speed-the-Plow" by David Mamet
Released first greatest hits album <i>The Immaculate Collection</i>
Subject of Alek Keshishian's documentary feature "Truth or Dare" (behind-the-scenes record of her Blond Ambition concert tour)
Signed a new recording contract with Time Warner; Madonna was to receive an approximate $25 million advance for each of her next seven records and her royalty was to be raised to 20 percent
Announced a seven-year agreement with Time Warner for Madonna to form her own multi-media entertainment company, Maverick; the company would be run by Madonna and her long-time manager Freddy DeMann
Released the book <i>Sex</i>; a volume consisting of erotic photographs and erotic literature by Madonna
First film released by Maverick (with Miramax), "Farewell My Concubine"
Was the subject of an unauthorized TV-movie biopic "Madonna: Innocence Lost" (Fox)
Portrayed the role of Eva Peron in the film musical "Evita"; the soundtrack album contained three of her singles
Formed MADGUY Productions
Entered into recording distribution agreement for her Maverick Records label with Lawrence Bender and Quentin Tarantino's newly formed A Band Apart Records
Co-wrote "Beautiful Stranger" for the soundtrack of "Austin Powers: The Spy Who Shagged Me"
Starred opposite Rupert Everett in "The Next Best Thing"
Debuted controversial music video "What It Feels Like for a Girl"; video directed by husband Guy Ritchie
Directed by husband Guy Ritchie in "Star," one of five short film advertisements for BMW shown over the Internet at bmwfilms.com
Released second greatest hits package <i>GHV2</i>
Made London stage acting debut in "Up for Grabs"
Starred in a remake of Lina Wertmuller's "Swept Away"; feature directed by husband Guy Ritchie
Composed and performed the title song for the James Bond film "Die Another Day"; song was nominated for two Grammy awards
Executive produced the action feature "Agent Cody Banks"
Was selected as the GAP spokesperson
Executive produced "Agent Cody Banks 2: Destination London"
Headlined the 14-city "Re-Invention Tour," which featured songs from her entire career
Voiced Princess Selenia in the animated feature directed by Luc Besson, "Arthur and the Invisibles"
Released the dance-oriented album <i>Confessions On a Dance Floor</i>; began touring in the U.S. and then internationally in May of 2006; received three Grammy nominations
First appearance at a music festival, performed at the Coachella Valley Music & Arts Festival in Indio, CA
Sold Maverick Record label to Warner Music Group 12 years after she founded it
Made directorial debut with "Filth and Wisdom," a film that revolves around a Ukrainian immigrant who finances his dreams of rock glory by moonlighting as a cross-dressing dominatrix
Inducted into the Rock and Roll Hall of Fame (March 10)
Released the album <i>Hard Candy</i>
Earned two Grammy nominations for her album <i>Hard Candy</i>, including one for her collaboration with Justin Timberlake on the song "4 Minutes"
Wrote and produced the documentary "I Am Because We Are," about the orphans in Malawi
Released her third greatest hits album <i>Celebration</i> with the new songs "Celebration" and "Revolver"; earned a Grammy nomination for Best Dance Recording for "Celebration"
Released her third live album <i>Sticky & Sweet Tour</i>; her first release under Live Nation
Directed second feature "W.E."; also co-wrote screenplay with Alek Keshishian
Released 12th studio album, <i>MDNA</i>, featuring the single "Give Me All Your Lovin'." Performed at the halftime show of Super Bowl XLVI.
Completed short film "secretprojectrevolution"