Made first stage appearance (unexpectedly) at age 3; recited "Old Mother Hubbard"
Broadway debut as chorus girl in "The Night Boat"
Appeared in a number of Broadway musicals during the 1920s, including "The Magic Ring", "Yes, Yes, Yvette", "Tip Toes", "Boom Boom", "Bubbling Over", "Sunny Days", and "Angela"
Reportedly seen by Paramount film star Richard Dix, who asked the studio to give her a screen test
Made unsuccessful Paramount screen test
Signed contract with Paramount after Ernst Lubitsch saw the screen test
Made film debut opposite Maurice Chevalier in Lubitsch's "The Love Parade"
Journeyed to Europe to give concerts in Paris and London to dispel rumor that she had been killed by the irate wife of a prince with whom MacDonald was supposedly having an affair and that her "twin sister" had taken over her screen career
Made last film at Paramount, "Love Me Tonight", opposite Chevalier
Set sail for Europe in December to give more extended concert tour
Signed contract with MGM
Last of 4 films opposite Chevalier, Lubitsch's "The Merry Widow"
First film opposite Nelson Eddy, "Naughty Marietta"
Appeared in most successful MGM film sans Eddy, "San Francisco"; that same year MacDonald made motion pictures exhibitors' poll of top ten boxoffice stars, placing 8th
Starred in "Smilin' Through" opposite her husband, Gene Raymond
Last of 8 films opposite Eddy, "I Married an Angel"
Final film under MGM contract, "Cairo"
Made opera debut in Montreal in "Romeo and Juliet" opposite Ezio Pinza
Appeared mostly in concert tours, opera and on radio during 1940s; also kept busy with war benefits and charity performances
Set a concert attendance record at the Hollywood Bowl
Returned to film after four-year absence in "Three Daring Daughters"
Last film appearance, opposite Claude Jarman Jr. and Lassie, in "The Sun Comes Up"
Collapsed while watching husband Gene Raymond performing in a play; rushed to hospital with appendicitis; later developed hepatitis
Had arterial transplant performed