Debuted on Broadway in David Storey's "The Changing Room"; won both the Tony and Drama Desk Awards
Executive produced and had title role in the TNT production "Don Quixote"
Starred in "Dirty Rotten Scoundrels," the Broadway musical adapted from the 1988 movie starring Michael Caine and Steve Martin; received a Tony nomination for his role
Voiced Lord Farquaad in the animated feature "Shrek"
Acted in the teen comedy "Orange County"
Began stage career as a director with the McCarter Theatre (operated by his father)
Delivered an Emmy-winning turn as a bachelor whose life is altered when he buys 'The Doll'; a segment of the NBC anthology series "Amazing Stories"
First collaboration with Brian De Palma, "Obsession"
Joined the fourth season of the Showtime series "Dexter" as Arthur Mitchell, a serial killer
Originated the lead role of a French diplomat in love with a Chinese opera singer in the Broadway production of "M. Butterfly"; earned a Tony Award nomination for Featured Actor in a Play
Played Colonel Bruce Derringer in the World War II drama "Memphis Belle"
Played Joe Keller in a Broadway revival of Arthur Miller's "All My Sons"
Played the moralistic anti-dancing, anti-rock pastor in "Footloose"
Appeared (also sang and wrote music) in a music video for children, "John Lithgow's Kid-Size Concert"
Cast in the Broadway production of "The Retreat from Moscow"
Earned a Tony Award nomination for Featured Actor in the Broadway production of "Requiem for a Heavyweight"
Earned second Best Supporting Actor Oscar nomination for his turn as a lawyer who enters into an affair with Debra Winger's character in "Terms of Endearment"
First leading role in a feature, the George Miller-directed remake of the classic Twilight Zone episode 'Nightmare at 20,000 Feet' in "Twilight Zone: The Movie"
Made stage debut at age six, in his father's production of "Henry VI, Part III"
Played the role of J.J. Hunsecker in the Broadway production of Marvin Hamlisch's "Sweet Smell of Success"
Played Walter Burns in the Lincoln Center Broadway revival of "The Front Page"
Portrayed Blake Edwards in the HBO movie "The Life and Death of Peter Sellers"
Portrayed the title character's moralistic, rigid father, opposite Liam Neeson in Bill Condon's "Kinsey"
Received a Grammy nomination for Best Spoken word for <i>The World According to Mr. Rogers</i> and <i>Carnival of the Animals</i>
Starred on Broadway opposite Lynn Redgrave in "My Fat Friend" and opposite Meryl Streep in Arthur Miller's "A Memory of Two Mondays"
Was the villain who hunted Sylvester Stallone in the action-thriller "Cliffhanger"
Won a Fulbright Scholarship to study drama in England
Breakthrough role, playing the transsexual football player in "The World According to Garp"; earned first Best Supporting Actor Oscar nomination
Cast as Dr. Dick Solomon, an extraterrestrial scientist and the High Commander on the NBC sitcom "3rd Rock from the Sun"; received Golden Globe (1998, 1999), Emmy (1998, 2000, 2001) and SAG (2001) nominations for his role
Feature acting debut, "Dealing: Or the Berkeley-to-Boston Forty-Brick Lost-Bag Blues"
Offered a brilliant dual performance in the psychological thriller "Raising Cain"
Starred as George S. Kaufman in a one-man off-Broadway show "Kaufman at Large"
Cast as Barney's (Neil Patrick Harris) father on two episodes of CBS' "How I Met Your Mother"
Played James F¿¿¿¿¿¿¿ranco's Alzheimers-stricken father in "Rise Of The Planet of the Apes"
Cast in the ensemble romantic comedy "New Year's Eve," directed by Garry Marshall
Starred on Broadway in "The Columnist," by Tony and Pulitzer Prize winner David Auburn
Featured opposite Paul Rudd and Leslie Mann in "This Is 40," directed by Judd Apatow
Played the White Rabbit on the Canadian series "Once Upon a Time in Wonderland"
Appeared in the acclaimed film "Interstellar"
Portrayed Winston Churchill on the series "The Crown"