Played Ramonda in Marvel's "Black Panther"
Returned to the Marvel Cinematic Universe in "Avengers: Infinity War"
Made her first foray into the "Mission: Impossible" franchise with "Mission: Impossible - Fallout"
Cast in Bob Dylan film "Masked & Anonymous"
First film with independent writer-director John Sayles, "City of Hope"
Portrayed the mother of a young girl trying to make it to the National Spelling Bee in "Akeelah and the Bee"
Cast as a school principal in "Music of the Heart"
Cast as Robert De Niro's love interest in "The Score"
First primetime TV guest spot, "Spenser: For Hire" (ABC)
Acted in Broadway production of August Wilson's "Joe Turner's Come and Gone," directed by Lloyd Richards
Appeared in less than stellar sci-fi flick "Supernova"
Joined cast of "Alias" (ABC) as the new CIA director
Played the owner of a waterfront joint in 1960s Louisiana who begins a relationship with a white male singer in Showtime movie "Ruby's Bucket of Blood"; also served as co-producer
Provided voice of writer Zora Neale Hurston for TBS documentary miniseries "A Century of Women"
Reprised role of Betty Shabazz for uncredited cameo in Mario Van Peebles' "Panther"
Appeared on episodes of "Spenser: For Hire" spin-off "A Man Called Hawk" (ABC)
Co-starred in female ensemble "Waiting to Exhale," directed by Forest Whitaker and scripted by Terry McMillan
Co-starred with Danny Glover in "Boesman and Lena"; film adapted from Athol Fugard's play
Starred in "Sunshine State" with Edie Falco as a failed actress who goes with her friend home to their northern Florida town
Portrayed Jackson family matriarch Katherine in ABC miniseries "The Jacksons: An American Dream"
Joined cast of NBC's "ER" as Dr. Cate Banfield, an exacting Chief of the ER; husband Courtney Vance played her television husband
Played Dr. Amanda Waller, a government agent in film adaptation of DC Comics superhero "Green Lantern"
Landed supporting role in "This Means War," an action comedy starring Reese Witherspoon, Chris Pine, and Tom Hardy
Played the head of the Secret Service in action thriller "Olympus Has Fallen"
Nabbed a supporting role in the crime-thriller "Survivor"
Nabbed a supporting role on the mini-series "Close to the Enemy"
Performed in the Hartford Stage Company production of "The Mystery Plays"
Made her Broadway debut in Lloyd Richards-directed production of August Wilson's "Ma Rainey's Black Bottom"
Made her feature film debut as a TV reporter in "F/X"
Co-starred in "Tyler Perry's Meet the Browns"
First gained notice as Laurence Fishburne's estranged wife in John Singleton's directorial debut, "Boyz n the Hood"
Portrayed Betty Shabazz, the wife of "Malcolm X," in Spike Lee's feature biopic
Starred in title role of CBS biopic "The Rosa Parks Story"
Delivered breakout role as Tina Turner (opposite Fishburne's Ike) in biopic "What's Love Got To Do With It"
Headlined second adaptation of a McMillan novel "How Stella Got Her Groove Back"
Portrayed Voletta Wallace, mother of slain rapper Biggie Smalls, in biopic "Notorious"
Made TV-movie debut as a prostitute in "Doubletake" (CBS)
Voiced U.S. First Lady Michelle Obama on "The Simpsons" (Fox) episode titled "Stealing First Base"
Co-starred with Samuel L. Jackson on Broadway in "The Mountaintop," a fictionalized depiction of the night before Dr. Martin Luther King's assassination
Co-starred in Spike Lee's "Chi-Raq"
Was a recurring character on Ryan Murphy's "American Horror Story"
Guest-starred on Aziz Ansari's "Master of None"