Moved with family 12 times before she was a senior in high school
Embarked upon travels through North and South America and Europe with first husband, photographer Paco Grande
Settled in New York where she danced and painted; joined Ellie Klein Theatre Group
Spent two years in Paris where she studied mime under Marcel Marceau's teacher, Etienne Decroux
Returned to New York where she waited tables and modeled with the Wilhelmina Agency
Signed seven-year contract with Dino De Laurentiis
Film debut in "King Kong"
Cast as the Angel of Death in Bob Fosse's autobiographical "All That Jazz"
Theater debut in summer stock production of "Angel on My Shoulder" in North Carolina
Delivered a sizzle turn as the unfaithful wife Cora opposite Jack Nicholson in the remake of "The Postman Always Rings Twice"
Became first actress since 1942 to be nominated for two Oscars in the same year; nominated for Best Actress for "Frances" and Best Supporting Actress for "Tootsie"; won the latter award
First film as co-producer, "Country"; earned second Best Actress Oscar nomination
TV acting debut as Maggie in the Showtime production of Tennessee Williams' "Cat on a Hot Tin Roof"
Received a Best Actress Academy Award nomination for her portrayal of country singer Patsy Cline in "Sweet Dreams"
Starred in "Far North"; directed by off-screen companion Sam Shepard
Garnered a Best Actress Oscar nod for her performance as a lawyer defending her father against charges he was a Nazi collaborator in "The Music Box"
Teamed with Nick Nolte and Robert De Niro for Martin Scorsese's remake of "Cape Fear"
Starred opposite De Niro in "Night and the City"
Broadway debut as Blanche DuBois in "A Streetcar Named Desire"
Played lead role of Alexandra Bergson in the CBS adaptation of Willa Cather's "O Pioneers!"
Won second Oscar as Best Actress for her performance in "Blue Sky"
Played wife to Liam Neeson's "Rob Roy"
Reprised Blanche DuBois for small screen adaptation of "A Streetcar Named Desire" (CBS)
Made London stage debut as Blanche in "A Streetcar Named Desire"
Played title role in film version of Balzac's "Cousin Bette"
Tackled first Shakespearean role as Tamora opposite Anthony Hopkins in "Titus," Julie Taymor's feature directorial debut
Returned to the London stage to star as Mary Tyrone in "Long Day's Journey Into Night"
Co-starred in the HBO movie "Normal"; received Emmy and Golden Globe nominations for Best Actress in a Television Movie
Portrayed the heroine's mother in the film version of "Prozac Nation"
Joined an ensemble cast for the feature "Masked and Anonymous"
Played wife to Albert Finney in "Big Fish"
Cast as an ex-flame of Bill Murray's in Jim Jarmusch's "Broken Flowers"
Portrayed Amanda Wingfield in Tennessee Williams' "The Glass Menagerie" on Broadway
Cast in Wim Wenders' neo-Western "Don't Come Knocking," written by and starring Sam Shepard
Co-starred with Joan Allen and Kathy Bates in the drama "Bonneville"
Portrayed Edith Ewing Bouvier 'Big Edie,' opposite Drew Barrymore as 'Little Edie,' in HBO "Grey Gardens"; earned Golden Globe and SAG nominations for Best Actress in a TV Movie
Co-starred with Dylan McDermott and Connie Britton on FX thriller "American Horror Story"
Featured opposite Rachel McAdams and Channing Tatum in romantic drama "The Vow"
Cast in lead role as Sister Mary Jude on "American Horror Story: Asylum" (FX)
Appeared in the thriller "In Secret"