Worked as a singing waitress one summer during college; travelled to Scotland as a member of the Ann Arbor Mime Troupe, then went to London, appearing in a mime production of Shakespeare's "The Tempest"
Moved to New York City; supported herself as a waitress by day and performed off-off Broadway by night; even worked as a mime for a while in Central Park, battling an imaginary wind as her roommate honked inexpertly on a clarinet
Appeared in commercials first for rug shampoo Spray 'n Vac, then for eight other products including Sominex and Joy dishwashing liquid
First Off-Broadway appearance as the female lead opposite Chris Sarandon in David Mamet's "The Woods" at the New York Shakespeare Festival's Public Theater
TV debut as Tania Reston in live-action, comic book adventure (movie-series pilot) "Dr Scorpion"
Had regular role as Harvey Korman's daughter in short-lived ABC sitcom "The Harvey Korman Show"
Feature film acting debut in "... And Justice For All"
Succeeded Roxane Hart opposite Kevin Kline in Michael Weller's Off-Broadway play, "Loose Ends"
Made Broadway debut in Steve Tesich's "Division Street"
Turned in excellent portrayal of a doctor in John Badham's feature "Whose Life Is It Anyway?"
Played Brenda Nicol in NBC miniseries "The Executioner's Song", based on the Norman Mailer book
Breakthrough film role in "Swing Shift" earned her a Best Supporting Actress Oscar nomination
Her Emmy nomination (Best Supporting Actress) was perhaps the lone high point of the ABC miniseries "Amerika", a ponderous 14-hour epic which incurred the wrath of the UN and USSR before airing
Delivered a wonderful performance as the free-spirited aunt in the underrated Housekeeping"
Starred with River Phoenix and Judd Hirsch in Sidney Lumet's "Running on Empty"
Appeared on Broadway (replacing Joan Allen) in Wendy Wasserstein's "The Heidi Chronicles"
Won a CableACE Award for Best Actress for her performance in the TNT movie "Crazy from the Heart", directed by husband Thomas Schlamme
Acted opposite William Hurt in "The Doctor"
Was atypically insufferable in the female buddy flick "Leaving Normal"
Starred with Ron Rifkin in the Off-Broadway production of Jon Robin Baitz's "Three Hotels"
Replaced Mandy Patinkin as a star of CBS drama "Chicago Hope", playing ambitious cardio-thoracic surgeon Dr Kathryn Austin; left series in spring of 1999
Directorial debut, "Lieberman in Love", earned her an Oscar for Best Live-Action Short Film; also starred opposite Danny Aiello; film aired on Showtime cable network
Starred in TNT movie "Hope", directed by "Swing Shift" co-star Goldie Hawn
Signed to make feature directorial debut with "My First Mister"
Had leading role of a US Senator's daughter nominated to be Surgeon General in the Lifetime adaptation of "An American Daughter" based on Wendy Wasserstein's play
Feature directorial debut, "My First Mister", screened at Sundance
Cast in lead role of a female Jewish doctor who survived the Holocaust in the Showtime biopic "Out of the Ashes"
Cast as Grace McCallister in the WB drama "Jack and Bobby"; received Golden Globe (2004) and SAG (2005) nominations for Best Actress in a Drama Series
Cast as a minister and bible scholar in the Playwrights Horizons production of Keith Bunin's "The Busy World is Hushed"
Will play a recurring role on "Law & Order: SVU" (NBC) as assistant district attorney