Appeared in the ensemble of "Ocean's Eleven"
Co-starred in "The Last Kiss," directed by Tony Goldwyn and scripted by Paul Haggis
Feature film debut as murdering teen in "To Die For"
Played a private investigator in brother Ben's feature directing debut "Gone, Baby, Gone"
Played supporting role in "Good Will Hunting," co-written and co-starring his brother Ben and Matt Damon
Re-teamed with the original cast for "Ocean's 13"
Acted in "Soul Survivors"
Appeared alongside brother Ben in "Chasing Amy"
Had co-starring role in "Drowning Mona"
Played Young Bobby Kennedy in the ABC miniseries "The Kennedys of Massachusetts"
Was featured in the Sundance-screened "Committed"
Co-starred as Robert Ford opposite Brad Pitt in "The Assassination of Jesse James by the Coward Robert Ford"; earned Golden Globe, SAG and Oscar nominations for Best Supporting Actor in a Motion Picture
Reunited with original cast for "Ocean's Twelve"; again directed by Steven Soderbergh
Cast in the indie film "200 Cigarettes," also featuring his brother Ben
Directed a series of interstitials for the Sundance Channel that were later compiled into "The Untitled Jay Lacopo Project"
Had youthful TV role in PBS' "American Playhouse" production of "Lemon Sky," starring Kevin Bacon
Played a 27-year-old who moves back in with his parents in Steve Buscemi's "Lonesome Jim"
With Matt Damon, co-starred in and co-wrote the Sundance-screened "Gerry"
Played a 1950s Texas sheriff and sociopath opposite Jessica Alba and Kate Hudson in Michael Winterbottom's noirish drama "The Killer Inside Me"
Directed the music documentary "I'm Still Here"; film followed actor and producer Joaquin Phoenix's attempt at launching a rap music career; Affleck later revealed the film was a fake
Co-starred with Ben Stiller and Eddie Murphy in the ensemble comedy "Tower Heist"